Primary Identifier | MGI:5308434 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Kdm5b |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
Project Collection | EUCOMM |
description | Cell lines EPD0027_1_F07 and EPD0027_1_F08 were successfully used to make chimeric mice. Germline transmission was accomplished. J:180267 |
molecularNote | The L1L2_gt0 cassette was inserted at position 136491938 of Chromosome 1 upstream of the critical exon(s) (Build 37). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 136492740. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele. |