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Allele : Fshb<tm1Zuk> follicle stimulating hormone beta; targeted mutation 1, Martin M Matzuk

Primary Identifier  MGI:1857434 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fshb
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  An HPRT minigene replaced a genomic fragment containing exons 1, 2 and part of 3. Northern blot analysis on RNA derived from pituitary of homozygous mice demonstrated that no detectable transcript was produced from thia allele. Radioimmunoasays on serum from homozygous mice confirmed that no functional protein was expressed from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • FSHbeta<->,
  • FSHbetaKO,
  • fshb<m1>,
  • fshb<m1>,
  • FSHbetaKO,
  • FSHbeta<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

34 Publication categories