| Primary Identifier | MGI:95582 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 14308 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable follicle-stimulating hormone activity. Acts upstream of or within several processes, including gonad development; positive regulation of bone resorption; and regulation of osteoclast differentiation. Located in cytoplasm. Is expressed in adenohypophysis pars anterior and pituitary gland. Human ortholog(s) of this gene implicated in amenorrhea and hypogonadotropic hypogonadism 24 without anosmia. Orthologous to human FSHB (follicle stimulating hormone subunit beta). PHENOTYPE: Females homozygous for a targeted null mutation are sterile with a preantral block in folliculogenesis. Mutant males have small testes and reduced Sertoli and germ cell numbers, but are fertile. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
