| Primary Identifier | MGI:6287205 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Arhgef10 |
| Transmission | Germline | Strain of Origin | 129S1/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exons 4 and 5. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed exons 4 and 5 and the selection cassette. Western blot analysis confirmed the absence of protein expression in the brain of adult homozygous mutant mice. |
