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Allele : Atr<tm1Ofc> ataxia telangiectasia and Rad3 related; targeted mutation 1, Oscar Fernandez-Capetillo

Primary Identifier  MGI:4355008 Allele Type  Targeted
Gene  Atr Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exons 8 through 10 were replaced with the corresponding human sequences. In addition, exon 9 contains an A to G transition that mimicks the mutation found in patients with Seckel syndrome. This mutation results in the skipping of this exon through abnormal splicing.
  • mutations:
  • Single point mutation,
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • ATR<S>,
  • ATR<seckel>,
  • ATR<S>,
  • ATR<seckel>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

16 Publication categories

Trail: Allele