Primary Identifier | MGI:4355008 | Allele Type | Targeted |
Gene | Atr | Transmission | Germline |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exons 8 through 10 were replaced with the corresponding human sequences. In addition, exon 9 contains an A to G transition that mimicks the mutation found in patients with Seckel syndrome. This mutation results in the skipping of this exon through abnormal splicing. |