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Protein Coding Gene : Rdh10 retinol dehydrogenase 10 (all-trans)
Primary Identifier  MGI:1924238 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  98711
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Enables all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within several processes, including chordate embryonic development; embryonic forelimb morphogenesis; and respiratory system development. Located in membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human RDH10 (retinol dehydrogenase 10).
PHENOTYPE: Embryos homozygous for null or hypomorphic alleles exhibit mid-gestational lethality, reduced Retinoic Acid signaling and abnormal limb, craniofacial, somite and cardiac morphology. [provided by MGI curators]
  • synonyms:
  • MGI:2138371,
  • D1Ertd762e,
  • mutation 366, Andrew S Peterson,
  • MGI:3799292,
  • AW549993,
  • 3110069K09Rik,
  • m366Asp,
  • MGI:1918069,
  • AI875664,
  • expressed sequence AI875664,
  • Rdh10,
  • 4921506A21Rik,
  • retinol dehydrogenase 10 (all-trans),
  • MGI:1289239,
  • expressed sequence AW549993,
  • MGI:2138606,
  • RIKEN cDNA 3110069K09 gene,
  • DNA segment, Chr 1, ERATO Doi 762, expressed,
  • RIKEN cDNA 4921506A21 gene
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