Primary Identifier | MGI:2154396 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bcr |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was partially replaced by insertion of a neomycin resistance expression cassette. Northern blot analysis with an exon 1 specific probe demonstrated that the transcript was not expressed in brain of homozygous mice, and western blot analysis on brain extracts showed that no protein was produced in homozygotes. |