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Allele : Bcr<tm1Hkp> BCR activator of RhoGEF and GTPase; targeted mutation 1, Nora Heisterkamp

Primary Identifier  MGI:2154396 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bcr
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was partially replaced by insertion of a neomycin resistance expression cassette. Northern blot analysis with an exon 1 specific probe demonstrated that the transcript was not expressed in brain of homozygous mice, and western blot analysis on brain extracts showed that no protein was produced in homozygotes.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

21 Publication categories