Primary Identifier | MGI:6200006 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Rasgrp1 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced A to T transversion at base pair 117,302,004 (v38) on chromosome 2, or base pair 40,874 in the GenBank genomic region NC_000068 encoding Rasgrp1. The mutation corresponds to residue 514 in the mRNA sequence NM_011246 within exon 4 of 17 total exons. The mutation results in substitution of lysine 116 for a premature stop codon (K116*). |