Primary Identifier | MGI:109573 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 21745 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables telomerase RNA binding activity. Contributes to telomerase activity. Predicted to be involved in telomere maintenance via recombination. Part of telomerase holoenzyme complex. Is expressed in 2-cell stage embryo and 4-cell stage embryo. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and stomach cancer. Orthologous to human TEP1 (telomerase associated protein 1). PHENOTYPE: Mice homozygous for a disruption in this gene show no obvious phenotype. No changes are seen in telomerase activity or telomere length. [provided by MGI curators] |