Primary Identifier | MGI:7785183 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mir10b |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were inserted to flank the entire coding region of the gene. An adjacent frt-flanked puromycin selection cassette was removed via FLP-mediated recombination in the germline. Subsequent germline Cre-mediated recombination resulted in the complete deletion of the gene. Deletion of miR-10b did not alter the expression of Hoxd4 and Hoxd3 host/adjacent genes. |