Primary Identifier | MGI:2676804 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 387144 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within cellular response to ethanol; cellular response to forskolin; and response to oxygen levels. Is expressed in embryo and trunk. Orthologous to human MIR10B (microRNA 10b). PHENOTYPE: Homozygous null mice exhibit hyperglycemia, impaired glucose tolerance, insulin resistance, gut dysmobility, gut barrier dysfunction, and colon inflammation. Mice homozygous for a reporter allele are viable with no observed pathologies. [provided by MGI curators] |