| Primary Identifier | MGI:2447196 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Abcg2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 5.1 kb genomic fragment encompassing exons 3 through 6 was replaced with a pgk-hygro selection cassette inserted by homologous recombination. The deleted region encoded the majority of the ATP-binding domain. The absence of normal transcript was confirmed by Northern blot analysis of homozygous mutant mice. No protein was detected by Western blot analysis or by immunohistochemical staining. |
