| Primary Identifier | MGI:1855940 | Allele Type | Radiation induced |
| Gene | a | Inheritance Mode | Recessive |
| Strain of Origin | (C3H/HeH x 101/H)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | The al allele is recessive to A and ae and dominant to a. al/ae mice resemble ae/ae mice. As both al/al and al/Ay mice die prenatally, al and a may be deletions that overlap at a site that causes prenatal lethality. The al deletion does not extend as far as the closely linked Gdf5 locus (Lyon MF, 1985). |
| molecularNote | This allele comprises a 75 kb deletion defined by a probe from the parotid secretory protein gene, Psp and located between 25 kb and 575 kb from the Psp coding sequences. The deletion does not extend as far as the closely linked Gdf5 locus. Homozygotes die prenatally and al/Ay mice also die prenatally, suggesting these alleles overlap at a site causing prenatal lethality. |
