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SO Term : destruction_box [SO:0001805] Sequence Ontology

Namespace  sequence Obsolete  false
description  A conserved polypeptide motif that can be recognized by both Fizzy/Cdc20- and FZR/Cdh1-activated anaphase-promoting complex/cyclosome (APC/C) and targets a protein for ubiquitination and subsequent degradation by the APC/C. The consensus sequence is RXXLXXXXN.
  • synonyms:
  • destruction box,
  • D-box
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