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DO Term : oocyte/zygote/embryo maturation arrest 15 [DOID:0061317] Disease Ontology

Namespace  disease_ontology Obsolete  false
description  An oocyte/zygote/embryo maturation arrest that is characterized by severely impaired zygote formation despite ovulation proceeding normally and retrieved oocytes appearing normal that has_material_basis_in homozygous mutation in the TLE6 gene on chromosome 19p13.3.
  • synonyms:
  • OMIM:616814,
  • UMLS_CUI:C5567489,
  • preimplantation embryonic lethality 1,
  • PREMBL1,
  • OZEMA15,
  • ORDO:488191,
  • PREMBL,
  • 616814,
  • female infertility due to oocyte meiotic arrest
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