Primary Identifier | MGI:1196624 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 21399 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity and zinc ion binding activity. Acts upstream of or within erythrocyte differentiation and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; lung; and spleen. Orthologous to human TCEA1 (transcription elongation factor A1). PHENOTYPE: Homozygous null mice display impaired definitive erythropoiesis with loss of late stage erythroblasts, fetal liver hypoplasia, and embryonic lethality. [provided by MGI curators] |