Primary Identifier | MGI:891989 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 226304 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity and neuropeptide binding activity. Acts upstream of or within regulation of metabolic process. Predicted to be active in neuron projection and plasma membrane. Orthologous to human NPBWR1 (neuropeptides B and W receptor 1). PHENOTYPE: Homozygous null males develop adult-onset obesity, are hyperphagic, and have decreased energy expenditure and locomotor activity. Plasma levels of glucose, leptin and insulin are elevated in males. [provided by MGI curators] |