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Protein Coding Gene : Mybl1 myeloblastosis oncogene-like 1

Primary Identifier  MGI:99925 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  17864
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and promoter-specific chromatin binding activity. Involved in male meiosis I; positive regulation of DNA-templated transcription; and spermatogenesis. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human MYBL1 (MYB proto-oncogene like 1).
PHENOTYPE: Homozygous null mice of both sexes show growth retardation after birth and an impairment of serum antibody response. Male mutant mice are sterile due to a meiotic defect. While female mutant mice are fertile, breast development is impaired after pregnancy. [provided by MGI curators]
  • synonyms:
  • MGI:3512779,
  • myeloblastosis oncogene-like 1,
  • reproductive mutant 9, JAX Reproductive Mutagenesis Program,
  • Mybl1,
  • G1-419-6,
  • MGD-MRK-16727,
  • repro9,
  • A-myb

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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Literature

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