Primary Identifier | MGI:1917925 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 70675 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including endoplasmic reticulum membrane fusion; protein modification by small protein conjugation or removal; and protein-DNA covalent cross-linking repair. Predicted to act upstream of or within DNA repair and proteolysis. Is active in synapse. Used to study progeria. Orthologous to human VCPIP1 (valosin containing protein interacting protein 1). PHENOTYPE: Homozygous knockout leads to chromosomal instability and premature aging. [provided by MGI curators] |