Primary Identifier | MGI:1917925 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 70675 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including endoplasmic reticulum membrane fusion; protein modification by small protein conjugation or removal; and protein-DNA covalent cross-linking repair. Is active in synapse. Used to study progeria. Orthologous to human VCPIP1 (valosin containing protein interacting protein 1). PHENOTYPE: Homozygous knockout leads to chromosomal instability and premature aging. [provided by MGI curators] |