Primary Identifier | MGI:1333884 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 17681 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; roof of mouth development; and skeletal muscle organ development. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in nucleus. Is expressed in several structures, including embryo mesenchyme; ganglia; immune system; limb bud; and musculature. Orthologous to human MSC (musculin). PHENOTYPE: Mice homozygous for a targeted mutation are obtained at predicted Mendelian ratios and exhibit no obvious phenotypic abnormalities. [provided by MGI curators] |