Primary Identifier | MGI:1352508 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 29819 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including Hsp70 protein binding activity; RNA binding activity; and kinesin binding activity. Predicted to be involved in several processes, including anterograde dendritic transport of messenger ribonucleoprotein complex; positive regulation of long-term synaptic depression; and positive regulation of nervous system development. Predicted to be located in axon; dendritic shaft; and nuclear membrane. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including cytoplasmic stress granule; neuron projection; and neuronal cell body. Is expressed in several structures, including central nervous system; olfactory epithelium; retina; submandibular gland primordium; and tooth. Orthologous to human STAU2 (staufen double-stranded RNA binding protein 2). PHENOTYPE: Male mice homozygous for a hypomorphic gene trap allele show impaired motor coordination but increased motor learning capacity in the rotarod test. [provided by MGI curators] |