First Author | Buchner G | Year | 1999 |
Journal | Genomics | Volume | 62 |
Issue | 1 | Pages | 113-8 |
PubMed ID | 10585778 | Mgi Jnum | J:58925 |
Mgi Id | MGI:1350688 | Doi | 10.1006/geno.1999.6015 |
Citation | Buchner G, et al. (1999) Identification of a novel homolog of the Drosophila staufen protein in the chromosome 8q13-q21.1 region. Genomics 62(1):113-8 |
abstractText | We report the identification of a new transcript homologous to the Drosophila staufen protein. This transcript, named STAU2 (HGMW-approved gene symbol and name), maps to the chromosome 8q13-q21 region. The full-length STAU2 cDNA is 4058 bp and contains an open reading frame of 479 amino acids. Analysis of the predicted protein product indicated the presence of three double-stranded RNA-binding domains. Best-fit analysis revealed a 48.5% similarity to the Drosophila protein and a 59.9% similarity to the recently described mammalian homolog hStau, indicating that at least two different transcripts with homologies to the fly protein are present in mammals. Copyright 1999 Academic Press. |