| Primary Identifier | MGI:101845 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 17215 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Predicted to be involved in DNA metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; limb; myocardium layer; neural ectoderm; and retina. Orthologous to human MCM3 (minichromosome maintenance complex component 3). PHENOTYPE: Mice homozygous for a null or hypomorph alleles exhibit prenatal lethality. Fetal mice homozygous for a hypomorphic allele display anemia and replicative stress during fetal erythropoiesis. Mice heterozygous for null or hypomorph alleles display increased incidence of lymphomas. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
