| Primary Identifier | MGI:2443162 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 320011 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Predicted to be involved in ERAD pathway and protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum lumen and endoplasmic reticulum-Golgi intermediate compartment. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum. Orthologous to human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1). PHENOTYPE: Heterozygous KO reduces susceptibility to and morbidity of RNA virus infection. Homozygous KO is embryonic lethal. The peptide is a folding sensor for glycoproteins in the ER. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
