| Primary Identifier | MGI:2441772 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 226982 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity; GTPase activity; and nucleic acid binding activity. Predicted to be involved in regulation of translational initiation; ribosome assembly; and translational initiation. Is active in synapse. Orthologous to human EIF5B (eukaryotic translation initiation factor 5B). PHENOTYPE: Mice homozygous for a knock-out allele show embryonic growth retardation and lethality before implantation. In vitro outgrowth assays show that embryos fail to hatch from the zona pellucida and die after 3 days in culture, never forming blastocysts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
