| Primary Identifier | MGI:106927 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 16764 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity and double-stranded DNA binding activity. Involved in embryonic hindlimb morphogenesis and regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; limb bud; nervous system; and sensory organ. Used to study KINSSHIP syndrome. Human ortholog(s) of this gene implicated in KINSSHIP syndrome. Orthologous to human AFF3 (ALF transcription elongation factor 3). PHENOTYPE: Mice homozygous for a humanized allele exhibit decreased fetal size, intestine prolapse, polydactyly, and abnormal long bones. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
