Primary Identifier | MGI:2138283 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 98388 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sulfotransferase activity. Acts upstream of or within learning and long-term memory. Predicted to be located in Golgi membrane. Is expressed in brain and cortical plate. Orthologous to human CHST10 (carbohydrate sulfotransferase 10). PHENOTYPE: Homozygous mutation of this gene results in altered synaptic transmission and long term potentiation. Mutant animals exhibit impaired spatial learning and long term memory deficits. Mice homozygous for a different knock-out allele exhibit reduced male and female fertility. [provided by MGI curators] |