| Primary Identifier | MGI:98427 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 17082 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables interleukin-33 binding activity. Involved in several processes, including macrophage differentiation; positive regulation of macrophage activation; and regulation of cytokine production. Acts upstream of or within response to wounding. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; immune system; musculoskeletal system; skin; and visual system. Human ortholog(s) of this gene implicated in asthma and coronary artery disease. Orthologous to human IL1RL1 (interleukin 1 receptor like 1). PHENOTYPE: Mice homozygous for disruptions in this gene display an abnormal Th2 type inflammatory response. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
