| Primary Identifier | MGI:105074 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 110895 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Involved in transepithelial ammonium transport. Acts upstream of or within gastric acid secretion and glandular epithelial cell development. Predicted to be located in basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; gallbladder; genitourinary system; gut; and thymus. Orthologous to human SLC9A4 (solute carrier family 9 member A4). PHENOTYPE: Homozygous null mice display normal growth and survival but have gastric secretions with reduced acidity, mild gastric necrosis and apoptosis, and abnormal gastric mucosa with reduced numbers of parietal and chief cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
