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Protein Coding Gene : Slc9a2 solute carrier family 9 (sodium/hydrogen exchanger), member 2
Primary Identifier  MGI:105075 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  226999
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables sodium:proton antiporter activity. Involved in epithelial cell differentiation and regulation of intracellular pH. Acts upstream of or within protein localization; regulation of pH; and sodium ion transport. Located in apical plasma membrane. Is expressed in genitourinary system and skeleton. Orthologous to human SLC9A2 (solute carrier family 9 member A2).
PHENOTYPE: Gastric acid secretion is impaired in homozygous mutant mice. The gastric mucosa becomes inflamed and exhibits an altered cellular composition. Mutant mice do not breed well. [provided by MGI curators]
  • synonyms:
  • Slc9a2,
  • MGD-MRK-32115,
  • AV333884,
  • MGI:3036276,
  • MGI:1917419,
  • solute carrier family 9 (sodium/hydrogen exchanger), member 2,
  • RIKEN cDNA 2210416H12 gene,
  • RIKEN cDNA 4932415O19 gene,
  • 2210416H12Rik,
  • NHE2,
  • expressed sequence AV333884,
  • MGI:2138533,
  • 4932415O19Rik
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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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