Primary Identifier | MGI:102724 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 22019 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable exopeptidase activity; identical protein binding activity; and peptide binding activity. Predicted to be involved in intracellular amino acid homeostasis and protein catabolic process. Predicted to be located in nuclear body. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human TPP2 (tripeptidyl peptidase 2). PHENOTYPE: Engineered mutations of this gene result in decreased lifespan and symptoms of immunohematopoietic senescence. [provided by MGI curators] |