| Primary Identifier | MGI:2181669 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 227102 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in ceramide metabolic process; intracellular sphingolipid homeostasis; and sphingolipid biosynthetic process. Predicted to act upstream of or within negative regulation of ceramide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of serine palmitoyltransferase complex. Orthologous to human ORMDL1 (ORMDL sphingolipid biosynthesis regulator 1). PHENOTYPE: Homozygous null mice show normal intracellular calcium levels and granulation in mast cells upon activation and normal mast cell ceramide levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
