Primary Identifier | MGI:1861735 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 56363 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in cell differentiation. Predicted to act upstream of or within negative regulation of cell migration; negative regulation of cellular component organization; and wound healing, spreading of cells. Predicted to be located in membrane. Predicted to be active in extracellular region. Is expressed in several structures, including gut; nervous system; prostate gland; vibrissa; and white fat. Human ortholog(s) of this gene implicated in prostate cancer and urinary bladder cancer. Orthologous to human TMEFF2 (transmembrane protein with EGF like and two follistatin like domains 2). PHENOTYPE: Mice homozygous for a reporter allele display slow postnatal weight gain, decreased white adipose tissue amount, and complete lethality at weaning. [provided by MGI curators] |