|  Help  |  About  |  Contact Us

Protein Coding Gene : Mob4 MOB family member 4, phocein

Primary Identifier  MGI:104899 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  19070
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable kinase binding activity and protein-macromolecule adaptor activity. Predicted to be involved in negative regulation of hippo signaling. Is active in glutamatergic synapse and postsynapse. Is expressed in early conceptus; primary oocyte; and secondary oocyte. Orthologous to human MOB4 (MOB family member 4, phocein).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete embryonic lethality by E9.5. [provided by MGI curators]
  • synonyms:
  • Mobkl3,
  • MOB1, Mps One Binder kinase activator-like 3 (yeast),
  • Mob4,
  • MGI:1917702,
  • MGD-MRK-29052,
  • RIKEN cDNA 2610109B12 gene,
  • 2610109B12Rik,
  • MOB family member 4, phocein,
  • Prei3,
  • preimplantation protein 3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For