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Protein Coding Gene : Plcl1 phospholipase C-like 1
Primary Identifier  MGI:3036262 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  227120
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable GABA receptor binding activity and phosphatidylinositol phospholipase C activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within gamma-aminobutyric acid signaling pathway and regulation of GABAergic synaptic transmission. Predicted to be located in cytoplasm. Is expressed in nervous system and vibrissa. Orthologous to human PLCL1 (phospholipase C like 1 (inactive)).
PHENOTYPE: Homozygous null mutants display impaired motor coordination and decreased sensitivity to the sedative diazepam. [provided by MGI curators]
  • synonyms:
  • PLC-L,
  • C230017K02Rik,
  • PRIP-1,
  • RIKEN cDNA C230017K02 gene,
  • phospholipase C-like 1,
  • Plcl1
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2 Involved In Mutations

Trail: ProteinCodingGene

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