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Protein Coding Gene : Ica1l islet cell autoantigen 1-like
Primary Identifier  MGI:1917625 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  70375
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable protein domain specific binding activity. Acts upstream of or within spermatid development. Located in acrosomal vesicle. Orthologous to human ICA1L (islet cell autoantigen 1 like).
PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit reduced male fertility with oligospermia, globospermia, and abnormal spermiogenesis, sperm nucleus and mitochondrial sheath morphology. [provided by MGI curators]
  • synonyms:
  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 15,
  • 1700030B17Rik,
  • Ica1l,
  • RIKEN cDNA 1700030B17 gene,
  • Mutant line 3465 Cecilia Lo,
  • MGI:5648232,
  • b2b3465Clo,
  • Als2cr15,
  • Bench to Bassinet Program (B2B/CVDC), mutation 3465 Cecilia Lo,
  • islet cell autoantigen 1-like
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