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Protein Coding Gene : Klf7 Kruppel-like transcription factor 7 (ubiquitous)

Primary Identifier  MGI:1935151 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  93691
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within axon guidance; dendrite morphogenesis; and positive regulation of DNA-templated transcription. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including genitourinary system; gut; immune system; nervous system; and sensory organ. Orthologous to human KLF7 (KLF transcription factor 7).
PHENOTYPE: Homozygous null mice die within 3 days of life, showing lack of gastic milk, hypopnea, cyanosis, olfactory bulb hypoplasia, no response to tail clamping, impaired axon projection in the olfactory and visual systems, cerebral cortex and hippocampus, and reduced dendritic branching in the hippocampus. [provided by MGI curators]
  • synonyms:
  • 9830124P08Rik,
  • Klf7,
  • Kruppel-like transcription factor 7 (ubiquitous),
  • RIKEN cDNA 9830124P08 gene,
  • MGI:2445036

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For