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Protein Coding Gene : Crygf crystallin, gamma F
Primary Identifier  MGI:88526 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  12969
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be a structural constituent of eye lens. Acts upstream of or within eye development. Is expressed in embryo; eye; head; lens; and retina. Human ortholog(s) of this gene implicated in cataract 4 multiple types and cataract 7. Orthologous to human CRYGD (crystallin gamma D).
PHENOTYPE: Mice homozygous for a chemically-induced single point mutation exhibit homogeneous cataracts while heterozygotes display less severe rays and concentric circles of lens opacity. [provided by MGI curators]
  • synonyms:
  • crystallin, gamma F,
  • RIKEN cDNA 3110001K11 gene,
  • MGD-MRK-2171,
  • gamma crystalline-2 [homologous to rat gF-cry],
  • Crygf,
  • 3110001K11Rik,
  • MGD-MRK-2181,
  • Len-2,
  • MGI:1916514,
  • Cryg-2,
  • DGcry-2,
  • MGD-MRK-8837
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