Primary Identifier | MGI:2448715 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 227288 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chemokine binding activity and chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; neutrophil chemotaxis; and receptor internalization. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in bone marrow and lung. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease; pyelonephritis; and urinary tract infection. Orthologous to human CXCR1 (C-X-C motif chemokine receptor 1). PHENOTYPE: Mice homozygous for a gene disruption display normal morphology, clinical chemistry, hematology, and behavior. [provided by MGI curators] |