Primary Identifier | MGI:98930 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 22349 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; intestinal D-glucose absorption; and regulation of plasma membrane bounded cell projection organization. Located in several cellular components, including brush border; filopodium tip; and lamellipodium. Is expressed in several structures, including alimentary system; brain; egg cylinder; metanephros; and reproductive system. Orthologous to human VIL1 (villin 1). PHENOTYPE: Homozygous null mutants do not exhibit gross abnormalities or apparent defects of microvilli morphogenesis, however in one line, an increased sensitivity to colitis induced by dextran sulfate was observed. [provided by MGI curators] |