Primary Identifier | MGI:1928902 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 58184 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including epidermal growth factor receptor binding activity; nuclear receptor coactivator activity; and protein homodimerization activity. Acts upstream of or within cytokine-mediated signaling pathway. Located in P-body. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and sensory organ. Orthologous to human CNOT9 (CCR4-NOT transcription complex subunit 9). PHENOTYPE: Embryos homozygous for an ENU-induced allele exhibit abnormal nervous system and brain morphology, cranioedema, and caudal body truncation. Mice carrying a targeted allele exhibit embryonic lethality. [provided by MGI curators] |