| Primary Identifier | MGI:107469 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 18802 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G-protein alpha-subunit binding activity; guanyl-nucleotide exchange factor activity; and phosphatidylinositol phospholipase C activity. Acts upstream of or within acrosome reaction. Predicted to be located in cytosol and endoplasmic reticulum. Predicted to be active in plasma membrane. Is expressed in male reproductive gland or organ and nervous system. Orthologous to human PLCD4 (phospholipase C delta 4). PHENOTYPE: Males homozygous for a targeted null mutation are subfertile or sterile. Sperm from mutant males fail to initiate the acrosome reaction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
