Primary Identifier | MGI:98960 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 22420 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within several processes, including epithelial-mesenchymal cell signaling; nephron tubule morphogenesis; and positive regulation of macromolecule biosynthetic process. Located in cell surface and extracellular matrix. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human WNT6 (Wnt family member 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired decidualization with reduced uterine stromal cell proliferation. [provided by MGI curators] |