Primary Identifier | MGI:2449712 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 260298 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within maternal behavior; neuron differentiation; and positive regulation of gene expression. Located in nucleus. Is expressed in several structures, including aorta-gonad-mesonephros; liver; and nervous system. Orthologous to human FEV (FEV transcription factor, ETS family member). PHENOTYPE: Homozygous inactivation of this gene leads to partial lethality within the first week of life, causes impaired serotonergic neuron development, and results in increased anxiety-like and aggressive behavior in adulthood. [provided by MGI curators] |