Primary Identifier | MGI:1095410 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 22145 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in microtubule cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in early embryo; lung; nervous system; and retina layer. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 22. Orthologous to human TUBA4A (tubulin alpha 4a). PHENOTYPE: Homozygous knockout results in a low platelet count and spherical platelets. [provided by MGI curators] |