Primary Identifier | MGI:2652846 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 241118 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ligand-gated sodium channel activity. Acts upstream of or within behavioral fear response. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; brain; gut; male reproductive gland or organ; and spinal cord mantle layer. Orthologous to human ASIC4 (acid sensing ion channel subunit family member 4). PHENOTYPE: Homozygous knockout increases the fear response in the predator-odor induced fear test and increases anxiety in open field and elevated plus maze tests. [provided by MGI curators] |