| Primary Identifier | MGI:109350 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 20536 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chloride:bicarbonate antiporter activity. Acts upstream of or within regulation of intracellular pH. Located in plasma membrane. Is expressed in nervous system and testis. Orthologous to human SLC4A3 (solute carrier family 4 member 3). PHENOTYPE: Homozygotes for one knock-out allele show inner retina defects including selective ERG b-wave depression, optic nerve and retinal vessel anomalies, sheathing of retinal vessels and late onset photoreceptor death. Homozygotes for another knock-out allele are more sensitive to seizure-inducing agents. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
